JYLAMVO vs OTREXUP

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	JYLAMVO	OTREXUP
Rating	New	New
Pharmacy pays	~$4.92 /30	~$4.92 /30
Type	RX	RX
Active ingredient	METHOTREXATE	METHOTREXATE
Manufacturer	Shorla	Assertio Speclty
Dosage forms	Solution	Injectable
Drug class	Folate Analog Metabolic Inhibitor	Folate Analog Metabolic Inhibitor
Boxed warning	Boxed warning	Boxed warning
Half-life	about 3 to 10 hours	about 3 to 10 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms	Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms

jylamvo otrexup

Rating

New

Pharmacy pays

~$4.92 /30

Type

Active ingredient

METHOTREXATE

Manufacturer

Shorla

Assertio Speclty

Dosage forms

Solution

Injectable

Drug class

Folate Analog Metabolic Inhibitor

Boxed warning

Half-life

about 3 to 10 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms

Frequently asked questions

Which is cheaper, Jylamvo or Otrexup?

Pharmacies pay about the same to acquire either one — roughly $4.92 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Jylamvo and Otrexup?

Both Jylamvo and Otrexup share the active ingredient Methotrexate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.