JUNIOR STRENGTH ADVIL vs ZIPSOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	JUNIOR STRENGTH ADVIL	ZIPSOR
Rating	72/100	New
Pharmacy pays	$0.04 /mL	$0.36 /mL
Type	OTC	RX
Active ingredient	IBUPROFEN	DICLOFENAC POTASSIUM
Manufacturer	Haleon US Holdings	Assertio Speclty
Dosage forms	Tablet, chewable, Tablet	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	Boxed warning
Half-life	about 1.8 to 2.0 hours	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

junior strength advil zipsor

Rating

72/100

New

Pharmacy pays

$0.04 /mL

$0.36 /mL

Type

OTC

Active ingredient

IBUPROFEN

DICLOFENAC POTASSIUM

Manufacturer

Haleon US Holdings

Assertio Speclty

Dosage forms

Tablet, chewable, Tablet

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Boxed warning

Half-life

about 1.8 to 2.0 hours

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

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Where to buy

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Frequently asked questions

Which is cheaper, Junior Strength Advil or Zipsor?

Junior Strength Advil costs pharmacies less to acquire — about $0.04 vs $0.36 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Junior Strength Advil and Zipsor?

Junior Strength Advil contains Ibuprofen, while Zipsor contains Diclofenac Potassium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.