JAKAFI XR vs LEQSELVI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. JAKAFI XR and LEQSELVI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	JAKAFI XR	LEQSELVI
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	RUXOLITINIB PHOSPHATE	DEURUXOLITINIB PHOSPHATE
Manufacturer	Incyte Corp	Sun Pharm Inds Inc
Dosage forms	Tablet, extended release	Tablet
Drug class	Janus Kinase Inhibitor	Janus Kinase Inhibitor
Boxed warning	None	Boxed warning
Treats	Polycythemia Vera, Primary Myelofibrosis	Alopecia Areata

jakafi xr leqselvi

Rating

New

Pharmacy pays

—

Type

Active ingredient

RUXOLITINIB PHOSPHATE

DEURUXOLITINIB PHOSPHATE

Manufacturer

Incyte Corp

Sun Pharm Inds Inc

Dosage forms

Tablet, extended release

Tablet

Drug class

Janus Kinase Inhibitor

Boxed warning

None

Boxed warning

Treats

Polycythemia Vera, Primary Myelofibrosis

Alopecia Areata

Frequently asked questions

What is the difference between Jakafi XR and Leqselvi?

Jakafi XR contains Ruxolitinib Phosphate, while Leqselvi contains Deuruxolitinib Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.