ISTURISA vs LYSODREN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ISTURISA and LYSODREN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ISTURISA	LYSODREN
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	OSILODROSTAT PHOSPHATE	MITOTANE
Manufacturer	Recordati Rare	Esteve
Dosage forms	Tablet	Tablet
Drug class	—	—
Boxed warning	None	Boxed warning
Treats	Cushing Syndrome	Cushing Syndrome, Adrenocortical Carcinoma

isturisa lysodren

Rating

New

Pharmacy pays

—

Type

Active ingredient

OSILODROSTAT PHOSPHATE

MITOTANE

Manufacturer

Recordati Rare

Esteve

Dosage forms

Tablet

Drug class

—

Boxed warning

None

Boxed warning

Treats

Cushing Syndrome

Cushing Syndrome, Adrenocortical Carcinoma

Frequently asked questions

What is the difference between Isturisa and Lysodren?

Isturisa contains Osilodrostat Phosphate, while Lysodren contains Mitotane — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.