ISTALOL vs TOPROL-XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ISTALOL and TOPROL-XL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ISTALOL	TOPROL-XL
Rating	New	New
Pharmacy pays	$1.06 /mL	~$0.58 /30
Type	RX	RX
Active ingredient	TIMOLOL MALEATE	METOPROLOL SUCCINATE
Manufacturer	Bausch and Lomb	Melinta Therap
Dosage forms	Drops	Tablet, extended release
Drug class	Beta-Adrenergic Blocker	Beta-Adrenergic Blocker
Boxed warning	None	None
Half-life	—	about 3 to 4 hours
Treats	Angina Pectoris, Open-Angle Glaucoma, Heart Failure	Angina Pectoris, Atrial Fibrillation, Atrial Flutter

istalol toprol-xl

Rating

New

Pharmacy pays

$1.06 /mL

~$0.58 /30

Type

Active ingredient

TIMOLOL MALEATE

METOPROLOL SUCCINATE

Manufacturer

Bausch and Lomb

Melinta Therap

Dosage forms

Drops

Tablet, extended release

Drug class

Beta-Adrenergic Blocker

Boxed warning

None

Half-life

—

about 3 to 4 hours

Treats

Angina Pectoris, Open-Angle Glaucoma, Heart Failure

Angina Pectoris, Atrial Fibrillation, Atrial Flutter

Get istalolhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

What is the difference between Istalol and Toprol-XL?

Istalol contains Timolol Maleate, while Toprol-XL contains Metoprolol Succinate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.