ISOVUE-300 vs OPTIRAY 350

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ISOVUE-300 and OPTIRAY 350 are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ISOVUE-300	OPTIRAY 350
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	IOPAMIDOL	IOVERSOL
Manufacturer	Bracco	Liebel-Flarsheim
Dosage forms	Injectable	Injectable
Drug class	Radiographic Contrast Agent	Radiographic Contrast Agent
Boxed warning	None	Boxed warning

isovue-300 optiray 350

Rating

New

Pharmacy pays

—

Type

Active ingredient

IOPAMIDOL

IOVERSOL

Manufacturer

Bracco

Liebel-Flarsheim

Dosage forms

Injectable

Drug class

Radiographic Contrast Agent

Boxed warning

None

Boxed warning

Frequently asked questions

What is the difference between Isovue-300 and Optiray 350?

Isovue-300 contains Iopamidol, while Optiray 350 contains Ioversol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.