ISOPTO CETAMIDE vs SILDAFLO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ISOPTO CETAMIDE and SILDAFLO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ISOPTO CETAMIDE	SILDAFLO
Rating	New	New
Pharmacy pays	$0.11 /g	$0.25 /g
Type	RX	RX
Active ingredient	SULFACETAMIDE SODIUM	SILVER SULFADIAZINE
Manufacturer	Alcon	Franklin Pharms
Dosage forms	Drops	Dressing
Drug class	Sulfonamide Antibacterial	Sulfonamide Antibacterial
Boxed warning	None	None
Treats	Corneal Ulcer, Ear Diseases, Seborrheic Dermatitis	Wound Infection

isopto cetamide sildaflo

Rating

New

Pharmacy pays

$0.11 /g

$0.25 /g

Type

Active ingredient

SULFACETAMIDE SODIUM

SILVER SULFADIAZINE

Manufacturer

Alcon

Franklin Pharms

Dosage forms

Drops

Dressing

Drug class

Sulfonamide Antibacterial

Boxed warning

None

Treats

Corneal Ulcer, Ear Diseases, Seborrheic Dermatitis

Wound Infection

Frequently asked questions

Which is cheaper, Isopto Cetamide or Sildaflo?

Isopto Cetamide costs pharmacies less to acquire — about $0.11 vs $0.25 per gm, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Isopto Cetamide and Sildaflo?

Isopto Cetamide contains Sulfacetamide Sodium, while Sildaflo contains Silver Sulfadiazine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.