IRESSA vs LORBRENA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. IRESSA and LORBRENA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IRESSA	LORBRENA
Rating	70/100	60/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	GEFITINIB	LORLATINIB
Manufacturer	Astrazeneca	Pfizer
Dosage forms	Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Non-Small-Cell Lung Carcinoma	—

iressa lorbrena

Rating

70/100

60/100

Pharmacy pays

—

Type

Active ingredient

GEFITINIB

LORLATINIB

Manufacturer

Astrazeneca

Pfizer

Dosage forms

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Non-Small-Cell Lung Carcinoma

—

Frequently asked questions

Which is better-rated, Iressa or Lorbrena?

By our independent rating, Iressa scores higher — 3.5 vs 3.0 out of 5 for Lorbrena. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Iressa and Lorbrena?

Iressa contains Gefitinib, while Lorbrena contains Lorlatinib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.