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INVEGA vs ZYPREXA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. INVEGA and ZYPREXA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

invegazyprexa

Rating

70/100
New

Pharmacy pays

~$32.99 /30
~$4.13 /30

Type

RX
RX

Active ingredient

PALIPERIDONE
OLANZAPINE

Manufacturer

Janssen Pharms
Cheplapharm

Dosage forms

Tablet, extended release
Tablet

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Boxed warning

Boxed warning
Boxed warning

Half-life

—
about 21 to 54 hours (mean around 30 hours)

Treats

Bipolar Disorder, Depressive Disorder, Schizophrenia
Bipolar Disorder, Psychotic Disorders, Schizophrenia

Get invegahigher-rated option

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Frequently asked questions

Which is cheaper, Invega or Zyprexa?

Zyprexa costs pharmacies less to acquire — about $4.13 vs $32.99 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Invega and Zyprexa?

Invega contains Paliperidone, while Zyprexa contains Olanzapine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.