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INVEGA vs SERENTIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. INVEGA and SERENTIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$31.99 /30
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Type

RX
RX

Active ingredient

PALIPERIDONE
MESORIDAZINE BESYLATE

Dosage forms

Tablet, extended release
Tablet

Drug class

Atypical Antipsychotic
—

Boxed warning

Treats

Bipolar Disorder, Depressive Disorder, Schizophrenia
Alcoholism, Psychotic Disorders, Schizophrenia

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Frequently asked questions

Which is better-rated, Invega or Serentil?

By our independent rating, Invega scores higher — 3.6 vs 3.5 out of 5 for Serentil. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Invega and Serentil?

Invega contains Paliperidone, while Serentil contains Mesoridazine Besylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.