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INVEGA vs RISPERDAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. INVEGA and RISPERDAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

invegarisperdal

Rating

70/100
70/100

Pharmacy pays

~$32.99 /30
~$2.07 /30

Type

RX
RX

Active ingredient

PALIPERIDONE
RISPERIDONE

Manufacturer

Janssen Pharms
Janssen Pharms

Dosage forms

Tablet, extended release
Solution, Tablet

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Boxed warning

Boxed warning
Boxed warning

Half-life

—
about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)

Treats

Bipolar Disorder, Depressive Disorder, Schizophrenia
Autistic Disorder, Bipolar Disorder, Dementia

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Frequently asked questions

Which is better-rated, Invega or Risperdal?

Invega and Risperdal are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Invega or Risperdal?

Risperdal costs pharmacies less to acquire — about $2.07 vs $32.99 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Invega and Risperdal?

Invega contains Paliperidone, while Risperdal contains Risperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.