INVEGA SUSTENNA vs UZEDY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. INVEGA SUSTENNA and UZEDY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	INVEGA SUSTENNA	UZEDY
Rating	70/100	56/100
Pharmacy pays	—	~$2.07 /30
Type	RX	RX
Active ingredient	PALIPERIDONE PALMITATE	RISPERIDONE
Manufacturer	Janssen Pharms	Teva
Dosage forms	Injectable	Injectable
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	—	about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)
Treats	Bipolar Disorder, Depressive Disorder, Schizophrenia	Autistic Disorder, Bipolar Disorder, Dementia

invega sustenna uzedy

Rating

70/100

56/100

Pharmacy pays

—

~$2.07 /30

Type

Active ingredient

PALIPERIDONE PALMITATE

RISPERIDONE

Manufacturer

Janssen Pharms

Teva

Dosage forms

Injectable

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

—

about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)

Treats

Bipolar Disorder, Depressive Disorder, Schizophrenia

Autistic Disorder, Bipolar Disorder, Dementia

Frequently asked questions

Which is better-rated, Invega Sustenna or Uzedy?

By our independent rating, Invega Sustenna scores higher — 3.5 vs 2.8 out of 5 for Uzedy. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Invega Sustenna and Uzedy?

Invega Sustenna contains Paliperidone Palmitate, while Uzedy contains Risperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.