Skip to content
ppharmaranks
Menu

IMODIUM vs SUBLIMAZE PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. IMODIUM and SUBLIMAZE PRESERVATIVE FREE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
72/100

Pharmacy pays

$0.05 /mL
$9.51 /mL

Type

RX
RX

Active ingredient

LOPERAMIDE HYDROCHLORIDE
FENTANYL CITRATE

Dosage forms

Capsule, Solution
Injectable

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

None
None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery
Pain

Frequently asked questions

Which is cheaper, Imodium or Sublimaze Preservative Free?

Imodium costs pharmacies less to acquire — about $0.05 vs $9.51 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Imodium and Sublimaze Preservative Free?

Imodium contains Loperamide Hydrochloride, while Sublimaze Preservative Free contains Fentanyl Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.