IMODIUM vs OXYCODONE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. IMODIUM and OXYCODONE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IMODIUM	OXYCODONE HYDROCHLORIDE
Rating	New	70/100
Pharmacy pays	$0.05 /mL	$0.08 /mL
Type	RX	RX
Active ingredient	LOPERAMIDE HYDROCHLORIDE	OXYCODONE HYDROCHLORIDE
Manufacturer	J and J Consumer Inc	Vistapharm LLC
Dosage forms	Capsule, Solution	Solution, Tablet, Tablet, extended release
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 10.8 hours (range 9.1 to 14.4 hours)	about 3.5 to 4 hours
Treats	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery	Postoperative Pain

imodium oxycodone hydrochloride

Rating

New

70/100

Pharmacy pays

$0.05 /mL

$0.08 /mL

Type

Active ingredient

LOPERAMIDE HYDROCHLORIDE

OXYCODONE HYDROCHLORIDE

Manufacturer

J and J Consumer Inc

Vistapharm LLC

Dosage forms

Capsule, Solution

Solution, Tablet, Tablet, extended release

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

about 3.5 to 4 hours

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

Postoperative Pain

Frequently asked questions

Which is cheaper, Imodium or Oxycodone Hydrochloride?

Imodium costs pharmacies less to acquire — about $0.05 vs $0.08 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Imodium and Oxycodone Hydrochloride?

Imodium contains Loperamide Hydrochloride, while Oxycodone Hydrochloride contains Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.