IMODIUM vs IMODIUM A-D

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Attribute	IMODIUM	IMODIUM A-D
Rating	New	70/100
Pharmacy pays	$0.05 /mL	$0.05 /mL
Type	RX	OTC
Active ingredient	LOPERAMIDE HYDROCHLORIDE	LOPERAMIDE HYDROCHLORIDE
Manufacturer	J and J Consumer Inc	Kenvue Brands
Dosage forms	Capsule, Solution	Capsule, Solution, Tablet
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 10.8 hours (range 9.1 to 14.4 hours)	about 10.8 hours (range 9.1 to 14.4 hours)
Treats	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

imodium imodium a-d

Rating

New

70/100

Pharmacy pays

$0.05 /mL

Type

OTC

Active ingredient

LOPERAMIDE HYDROCHLORIDE

Manufacturer

J and J Consumer Inc

Kenvue Brands

Dosage forms

Capsule, Solution

Capsule, Solution, Tablet

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

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Where to buy

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Frequently asked questions

Which is cheaper, Imodium or Imodium A-D?

Pharmacies pay about the same to acquire either one — roughly $0.05 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Imodium and Imodium A-D?

Both Imodium and Imodium A-D share the active ingredient Loperamide Hydrochloride, but Imodium is sold as RX and Imodium A-D as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.