IMODIUM A-D vs VANTRELA ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	IMODIUM A-D	VANTRELA ER
Rating	70/100	New
Pharmacy pays	$0.05 /mL	~$239.09 /30
Type	OTC	RX
Active ingredient	LOPERAMIDE HYDROCHLORIDE	HYDROCODONE BITARTRATE
Manufacturer	Kenvue Brands	Teva Branded Pharm
Dosage forms	Capsule, Solution, Tablet	Tablet, extended release
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 10.8 hours (range 9.1 to 14.4 hours)	about 3.8 hours (3.8 ± 0.3 hours)
Treats	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery	Cough, Obstructive Lung Diseases, Postoperative Pain

imodium a-d vantrela er

Rating

70/100

New

Pharmacy pays

$0.05 /mL

~$239.09 /30

Type

OTC

Active ingredient

LOPERAMIDE HYDROCHLORIDE

HYDROCODONE BITARTRATE

Manufacturer

Kenvue Brands

Teva Branded Pharm

Dosage forms

Capsule, Solution, Tablet

Tablet, extended release

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

about 3.8 hours (3.8 ± 0.3 hours)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

Cough, Obstructive Lung Diseases, Postoperative Pain

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Frequently asked questions

What is the difference between Imodium A-D and Vantrela ER?

Imodium A-D contains Loperamide Hydrochloride, while Vantrela ER contains Hydrocodone Bitartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.