IMODIUM A-D vs SUFENTA PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Attribute	IMODIUM A-D	SUFENTA PRESERVATIVE FREE
Rating	70/100	72/100
Pharmacy pays	$0.05 /mL	—
Type	OTC	RX
Active ingredient	LOPERAMIDE HYDROCHLORIDE	SUFENTANIL CITRATE
Manufacturer	Kenvue Brands	Rising
Dosage forms	Capsule, Solution, Tablet	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 10.8 hours (range 9.1 to 14.4 hours)	—
Treats	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery	Pain

imodium a-d sufenta preservative free

Rating

70/100

72/100

Pharmacy pays

$0.05 /mL

—

Type

OTC

Active ingredient

LOPERAMIDE HYDROCHLORIDE

SUFENTANIL CITRATE

Manufacturer

Kenvue Brands

Rising

Dosage forms

Capsule, Solution, Tablet

Injectable

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

—

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

Pain

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Frequently asked questions

Which is better-rated, Imodium A-D or Sufenta Preservative Free?

By our independent rating, Sufenta Preservative Free scores higher — 3.6 vs 3.5 out of 5 for Imodium A-D. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Imodium A-D and Sufenta Preservative Free?

Imodium A-D contains Loperamide Hydrochloride, while Sufenta Preservative Free contains Sufentanil Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.