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IMODIUM A-D vs MORPHINE SULFATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Rating

70/100
New

Pharmacy pays

$0.05 /mL
$2.61 /mL

Type

OTC
RX

Active ingredient

LOPERAMIDE HYDROCHLORIDE
MORPHINE SULFATE

Dosage forms

Capsule, Solution, Tablet
Tablet, Tablet, extended release

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)
about 2 hours

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery
Dyspnea, Intractable Pain

Get imodium a-dhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is cheaper, Imodium A-D or Morphine Sulfate?

Imodium A-D costs pharmacies less to acquire — about $0.05 vs $2.61 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Imodium A-D and Morphine Sulfate?

Imodium A-D contains Loperamide Hydrochloride, while Morphine Sulfate contains Morphine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.