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IMODIUM A-D vs IMODIUM A-D EZ CHEWS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Rating

70/100
New

Pharmacy pays

$0.05 /mL
$0.05 /mL

Type

OTC
RX

Active ingredient

LOPERAMIDE HYDROCHLORIDE
LOPERAMIDE HYDROCHLORIDE

Dosage forms

Capsule, Solution, Tablet
Tablet, chewable

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

None
None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)
about 10.8 hours (range 9.1 to 14.4 hours)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery
Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

Get imodium a-dhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is cheaper, Imodium A-D or Imodium A-D Ez Chews?

Pharmacies pay about the same to acquire either one — roughly $0.05 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Imodium A-D and Imodium A-D Ez Chews?

Both Imodium A-D and Imodium A-D Ez Chews share the active ingredient Loperamide Hydrochloride, but Imodium A-D is sold as OTC and Imodium A-D Ez Chews as RX.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.