IMODIUM A-D EZ CHEWS vs ULTRAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. IMODIUM A-D EZ CHEWS and ULTRAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IMODIUM A-D EZ CHEWS	ULTRAM
Rating	New	70/100
Pharmacy pays	$0.05 /mL	~$0.72 /30
Type	RX	RX
Active ingredient	LOPERAMIDE HYDROCHLORIDE	TRAMADOL HYDROCHLORIDE
Manufacturer	J and J Consumer Inc	Janssen Pharms
Dosage forms	Tablet, chewable	Tablet
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	about 10.8 hours (range 9.1 to 14.4 hours)	about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)
Treats	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery	Pain

imodium a-d ez chews ultram

Rating

New

70/100

Pharmacy pays

$0.05 /mL

~$0.72 /30

Type

Active ingredient

LOPERAMIDE HYDROCHLORIDE

TRAMADOL HYDROCHLORIDE

Manufacturer

J and J Consumer Inc

Janssen Pharms

Dosage forms

Tablet, chewable

Tablet

Drug class

Opioid Agonist

Boxed warning

None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

about 6 hours (mean terminal elimination half-life of tramadol in healthy adults)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

Pain

Frequently asked questions

What is the difference between Imodium A-D Ez Chews and Ultram?

Imodium A-D Ez Chews contains Loperamide Hydrochloride, while Ultram contains Tramadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.