Skip to content
ppharmaranks
Menu

IMODIUM A-D EZ CHEWS vs METHADOSE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. IMODIUM A-D EZ CHEWS and METHADOSE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$0.05 /mL
$0.18 /mL

Type

RX
RX

Active ingredient

LOPERAMIDE HYDROCHLORIDE
METHADONE HYDROCHLORIDE

Dosage forms

Tablet, chewable

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)
about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery
Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is cheaper, Imodium A-D Ez Chews or Methadose?

Imodium A-D Ez Chews costs pharmacies less to acquire — about $0.05 vs $0.18 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Imodium A-D Ez Chews and Methadose?

Imodium A-D Ez Chews contains Loperamide Hydrochloride, while Methadose contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.