IMITREX vs MAXALT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. IMITREX and MAXALT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IMITREX	MAXALT
Rating	72/100	72/100
Pharmacy pays	~$484.84 /30	—
Type	RX	RX
Active ingredient	SUMATRIPTAN	RIZATRIPTAN BENZOATE
Manufacturer	Glaxosmithkline	Organon
Dosage forms	Injectable, Tablet	Tablet
Drug class	Serotonin-1b and Serotonin-1d Receptor Agonist	Serotonin-1b and Serotonin-1d Receptor Agonist
Boxed warning	None	None
Half-life	about 2 hours (terminal elimination half-life 115 ± 19 minutes)	about 2 to 3 hours
Treats	Cluster Headache, Migraine Disorders	Migraine Disorders

imitrex maxalt

Rating

72/100

Pharmacy pays

~$484.84 /30

—

Type

Active ingredient

SUMATRIPTAN

RIZATRIPTAN BENZOATE

Manufacturer

Glaxosmithkline

Organon

Dosage forms

Injectable, Tablet

Tablet

Drug class

Serotonin-1b and Serotonin-1d Receptor Agonist

Boxed warning

None

Half-life

about 2 hours (terminal elimination half-life 115 ± 19 minutes)

about 2 to 3 hours

Treats

Cluster Headache, Migraine Disorders

Migraine Disorders

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Frequently asked questions

Which is better-rated, Imitrex or Maxalt?

Imitrex and Maxalt are tied at 3.6 out of 5 by our independent rating.

What is the difference between Imitrex and Maxalt?

Imitrex contains Sumatriptan, while Maxalt contains Rizatriptan Benzoate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.