IMIPRAMINE HYDROCHLORIDE vs NORTRIPTYLINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. IMIPRAMINE HYDROCHLORIDE and NORTRIPTYLINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IMIPRAMINE HYDROCHLORIDE	NORTRIPTYLINE HYDROCHLORIDE
Rating	70/100	68/100
Pharmacy pays	~$2.54 /30	$0.17 /mL
Type	RX	RX
Active ingredient	IMIPRAMINE HYDROCHLORIDE	NORTRIPTYLINE HYDROCHLORIDE
Manufacturer	Strides Pharma Intl	Aurobindo Pharma Ltd
Dosage forms	Tablet	Capsule, Solution
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	Boxed warning	None
Treats	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis	Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

imipramine hydrochloride nortriptyline hydrochloride

Rating

70/100

68/100

Pharmacy pays

~$2.54 /30

$0.17 /mL

Type

Active ingredient

IMIPRAMINE HYDROCHLORIDE

NORTRIPTYLINE HYDROCHLORIDE

Manufacturer

Strides Pharma Intl

Aurobindo Pharma Ltd

Dosage forms

Tablet

Capsule, Solution

Drug class

Tricyclic Antidepressant

Boxed warning

None

Treats

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

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Frequently asked questions

Which is better-rated, Imipramine Hydrochloride or Nortriptyline Hydrochloride?

By our independent rating, Imipramine Hydrochloride scores higher — 3.5 vs 3.4 out of 5 for Nortriptyline Hydrochloride. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Imipramine Hydrochloride and Nortriptyline Hydrochloride?

Imipramine Hydrochloride contains Imipramine Hydrochloride, while Nortriptyline Hydrochloride contains Nortriptyline Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.