IMBRUVICA vs REVLIMID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. IMBRUVICA and REVLIMID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IMBRUVICA	REVLIMID
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	IBRUTINIB	LENALIDOMIDE
Manufacturer	Pharmacyclics LLC	Bristol Myers Squibb
Dosage forms	Capsule, Suspension, Tablet	Capsule
Drug class	—	Thalidomide Analog
Boxed warning	None	Boxed warning
Half-life	—	about 3 hours in healthy subjects, and 3 to 5 hours in patients with multiple myeloma, MDS, or mantle cell lymphoma
Treats	Waldenstrom Macroglobulinemia, B-Cell Chronic Lymphocytic Leukemia, B-Cell Lymphoma	Multiple Myeloma, Myelodysplastic Syndromes, Mantle-Cell Lymphoma

imbruvica revlimid

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

IBRUTINIB

LENALIDOMIDE

Manufacturer

Pharmacyclics LLC

Bristol Myers Squibb

Dosage forms

Capsule, Suspension, Tablet

Capsule

Drug class

—

Thalidomide Analog

Boxed warning

None

Boxed warning

Half-life

—

about 3 hours in healthy subjects, and 3 to 5 hours in patients with multiple myeloma, MDS, or mantle cell lymphoma

Treats

Waldenstrom Macroglobulinemia, B-Cell Chronic Lymphocytic Leukemia, B-Cell Lymphoma

Multiple Myeloma, Myelodysplastic Syndromes, Mantle-Cell Lymphoma

Frequently asked questions

What is the difference between Imbruvica and Revlimid?

Imbruvica contains Ibrutinib, while Revlimid contains Lenalidomide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.