IGALMI vs ONTRALFY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. IGALMI and ONTRALFY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	IGALMI	ONTRALFY
Rating	New	New
Pharmacy pays	—	~$1.00 /30
Type	RX	RX
Active ingredient	DEXMEDETOMIDINE HYDROCHLORIDE	TIZANIDINE HYDROCHLORIDE
Manufacturer	Bioxcel	Fidelity Biopharma
Dosage forms	Film	Solution
Drug class	Central Alpha-2 Adrenergic Agonist	Central Alpha-2 Adrenergic Agonist
Boxed warning	None	None
Half-life	—	about 2.5 hours
Treats	Pain, Psychomotor Agitation	Muscle Cramp, Muscle Rigidity, Muscle Spasticity

igalmi ontralfy

Rating

New

Pharmacy pays

—

~$1.00 /30

Type

Active ingredient

DEXMEDETOMIDINE HYDROCHLORIDE

TIZANIDINE HYDROCHLORIDE

Manufacturer

Bioxcel

Fidelity Biopharma

Dosage forms

Film

Solution

Drug class

Central Alpha-2 Adrenergic Agonist

Boxed warning

None

Half-life

—

about 2.5 hours

Treats

Pain, Psychomotor Agitation

Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Frequently asked questions

What is the difference between Igalmi and Ontralfy?

Igalmi contains Dexmedetomidine Hydrochloride, while Ontralfy contains Tizanidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.