HYDROXYZINE HYDROCHLORIDE vs LORAZEPAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. HYDROXYZINE HYDROCHLORIDE and LORAZEPAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	HYDROXYZINE HYDROCHLORIDE	LORAZEPAM
Rating	New	72/100
Pharmacy pays	$0.04 /mL	~$1.14 /30
Type	RX	RX
Active ingredient	HYDROXYZINE HYDROCHLORIDE	LORAZEPAM
Manufacturer	Pliva	Ani Pharms
Dosage forms	Injectable, Solution, Syrup, Tablet	Injectable, Solution, Liquid, Tablet
Drug class	Antihistamine	Benzodiazepine
Boxed warning	None	Boxed warning
Half-life	about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours)	about 12 hours (mean)
Treats	Anxiety Disorders, Nausea, Pruritus	Anxiety Disorders, Catatonia, Depressive Disorder

hydroxyzine hydrochloride lorazepam

Rating

New

72/100

Pharmacy pays

$0.04 /mL

~$1.14 /30

Type

Active ingredient

HYDROXYZINE HYDROCHLORIDE

LORAZEPAM

Manufacturer

Pliva

Ani Pharms

Dosage forms

Injectable, Solution, Syrup, Tablet

Injectable, Solution, Liquid, Tablet

Drug class

Antihistamine

Benzodiazepine

Boxed warning

None

Boxed warning

Half-life

about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours)

about 12 hours (mean)

Treats

Anxiety Disorders, Nausea, Pruritus

Anxiety Disorders, Catatonia, Depressive Disorder

Frequently asked questions

What is the difference between Hydroxyzine Hydrochloride and Lorazepam?

Hydroxyzine Hydrochloride contains Hydroxyzine Hydrochloride, while Lorazepam contains Lorazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.