HYDROPRES 25 vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. HYDROPRES 25 and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	HYDROPRES 25	MYSOLINE
Rating	72/100	74/100
Pharmacy pays	~$0.91 /30	~$2.89 /30
Type	RX	RX
Active ingredient	HYDROCHLOROTHIAZIDE AND RESERPINE	PRIMIDONE
Manufacturer	Merck	Valeant Pharm Intl
Dosage forms	Tablet	Tablet
Drug class	—	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	about 6 to 15 hours (the label reports a range, not a single number)	—
Treats	—	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

hydropres 25 mysoline

Rating

72/100

74/100

Pharmacy pays

~$0.91 /30

~$2.89 /30

Type

Active ingredient

HYDROCHLOROTHIAZIDE AND RESERPINE

PRIMIDONE

Manufacturer

Merck

Valeant Pharm Intl

Dosage forms

Tablet

Drug class

—

Anti-Epileptic Agent

Boxed warning

None

Half-life

about 6 to 15 hours (the label reports a range, not a single number)

—

Treats

—

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

Which is better-rated, Hydropres 25 or Mysoline?

By our independent rating, Mysoline scores higher — 3.7 vs 3.6 out of 5 for Hydropres 25. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Hydropres 25 or Mysoline?

Hydropres 25 costs pharmacies less to acquire — about $0.91 vs $2.89 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Hydropres 25 and Mysoline?

Hydropres 25 contains Hydrochlorothiazide and Reserpine, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.