HYDRO-RIDE vs MODURETIC 5-50

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	HYDRO-RIDE	MODURETIC 5-50
Rating	70/100	70/100
Pharmacy pays	~$6.00 /30	~$6.00 /30
Type	RX	RX
Active ingredient	AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE	AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
Manufacturer	Par Pharm	Merck
Dosage forms	Tablet	Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	about 6 to 15 hours (the label reports a range, not a single number)	about 6 to 15 hours (the label reports a range, not a single number)

hydro-ride moduretic 5-50

Rating

70/100

Pharmacy pays

~$6.00 /30

Type

Active ingredient

AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE

Manufacturer

Par Pharm

Merck

Dosage forms

Tablet

Drug class

—

Boxed warning

None

Half-life

about 6 to 15 hours (the label reports a range, not a single number)

Frequently asked questions

Which is better-rated, Hydro-Ride or Moduretic 5-50?

Hydro-Ride and Moduretic 5-50 are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Hydro-Ride or Moduretic 5-50?

Pharmacies pay about the same to acquire either one — roughly $6.00 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Hydro-Ride and Moduretic 5-50?

Both Hydro-Ride and Moduretic 5-50 share the active ingredient Amiloride Hydrochloride and Hydrochlorothiazide.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.