HYCAMTIN vs ZEJULA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 13, 2026·How we rate

Possible drug interaction. HYCAMTIN and ZEJULA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	HYCAMTIN	ZEJULA
Rating	68/100	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	TOPOTECAN HYDROCHLORIDE	NIRAPARIB TOSYLATE
Manufacturer	Sandoz	Glaxosmithkline
Dosage forms	Capsule, Injectable	Tablet
Drug class	—	—
Boxed warning	Boxed warning	None
Treats	Non-Small-Cell Lung Carcinoma, Uterine Cervical Neoplasms, Ovarian Neoplasms	Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms

hycamtin zejula

Rating

68/100

70/100

Pharmacy pays

—

Type

Active ingredient

TOPOTECAN HYDROCHLORIDE

NIRAPARIB TOSYLATE

Manufacturer

Sandoz

Glaxosmithkline

Dosage forms

Capsule, Injectable

Tablet

Drug class

—

Boxed warning

None

Treats

Non-Small-Cell Lung Carcinoma, Uterine Cervical Neoplasms, Ovarian Neoplasms

Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms

Frequently asked questions

Which is better-rated, Hycamtin or Zejula?

By our independent rating, Zejula scores higher — 3.5 vs 3.4 out of 5 for Hycamtin. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Hycamtin and Zejula?

Hycamtin contains Topotecan Hydrochloride, while Zejula contains Niraparib Tosylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.