HORIZANT vs INVEGA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. HORIZANT and INVEGA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	HORIZANT	INVEGA
Rating	70/100	70/100
Pharmacy pays	—	~$32.99 /30
Type	RX	RX
Active ingredient	GABAPENTIN ENACARBIL	PALIPERIDONE
Manufacturer	Azurity	Janssen Pharms
Dosage forms	Tablet, extended release	Tablet, extended release
Drug class	—	Atypical Antipsychotic
Boxed warning	None	Boxed warning
Half-life	about 5 to 7 hours in adults with normal kidney function	—
Treats	Bipolar Disorder, Partial Epilepsies, Phobic Disorders	Bipolar Disorder, Depressive Disorder, Schizophrenia

horizant invega

Rating

70/100

Pharmacy pays

—

~$32.99 /30

Type

Active ingredient

GABAPENTIN ENACARBIL

PALIPERIDONE

Manufacturer

Azurity

Janssen Pharms

Dosage forms

Tablet, extended release

Drug class

—

Atypical Antipsychotic

Boxed warning

None

Boxed warning

Half-life

about 5 to 7 hours in adults with normal kidney function

—

Treats

Bipolar Disorder, Partial Epilepsies, Phobic Disorders

Bipolar Disorder, Depressive Disorder, Schizophrenia

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Frequently asked questions

Which is better-rated, Horizant or Invega?

Horizant and Invega are tied at 3.5 out of 5 by our independent rating.

What is the difference between Horizant and Invega?

Horizant contains Gabapentin Enacarbil, while Invega contains Paliperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.