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HEPSERA vs VIREAD

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. HEPSERA and VIREAD are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

hepseraviread

Rating

70/100
70/100

Pharmacy pays

~$673.35 /30
~$9.50 /30

Type

RX
RX

Active ingredient

ADEFOVIR DIPIVOXIL
TENOFOVIR DISOPROXIL FUMARATE

Manufacturer

Gilead Sciences Inc
Gilead Sciences Inc

Dosage forms

Tablet
Powder, Tablet

Drug class

—
Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor

Boxed warning

None
Boxed warning

Treats

Chronic Hepatitis B
Chronic Hepatitis B, Acquired Immunodeficiency Syndrome

Frequently asked questions

Which is better-rated, Hepsera or Viread?

Hepsera and Viread are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Hepsera or Viread?

Viread costs pharmacies less to acquire — about $9.50 vs $673.35 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Hepsera and Viread?

Hepsera contains Adefovir Dipivoxil, while Viread contains Tenofovir Disoproxil Fumarate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.