HALFAN vs PYRIMETHAMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. HALFAN and PYRIMETHAMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	HALFAN	PYRIMETHAMINE
Rating	70/100	68/100
Pharmacy pays	—	~$4110.26 /30
Type	RX	RX
Active ingredient	HALOFANTRINE HYDROCHLORIDE	PYRIMETHAMINE
Manufacturer	Glaxosmithkline	Aurobindo Pharma Ltd
Dosage forms	Tablet	Tablet
Drug class	—	Dihydrofolate Reductase Inhibitor Antimalarial
Boxed warning	None	None
Treats	Falciparum Malaria, Vivax Malaria	Toxoplasmosis, Falciparum Malaria, Aids-Related Opportunistic Infections

halfan pyrimethamine

Rating

70/100

68/100

Pharmacy pays

—

~$4110.26 /30

Type

Active ingredient

HALOFANTRINE HYDROCHLORIDE

PYRIMETHAMINE

Manufacturer

Glaxosmithkline

Aurobindo Pharma Ltd

Dosage forms

Tablet

Drug class

—

Dihydrofolate Reductase Inhibitor Antimalarial

Boxed warning

None

Treats

Falciparum Malaria, Vivax Malaria

Toxoplasmosis, Falciparum Malaria, Aids-Related Opportunistic Infections

Frequently asked questions

Which is better-rated, Halfan or Pyrimethamine?

By our independent rating, Halfan scores higher — 3.5 vs 3.4 out of 5 for Pyrimethamine. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Halfan and Pyrimethamine?

Halfan contains Halofantrine Hydrochloride, while Pyrimethamine contains Pyrimethamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.