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GYNE-LOTRIMIN 3 vs MONISTAT-DERM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 13, 2026·How we rate

Possible drug interaction. GYNE-LOTRIMIN 3 and MONISTAT-DERM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
70/100

Pharmacy pays

$0.21 /mL

Type

RX
RX

Active ingredient

CLOTRIMAZOLE
MICONAZOLE NITRATE

Dosage forms

Topical, Tablet
Topical

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Treats

Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis
Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis

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Frequently asked questions

Which is better-rated, Gyne-Lotrimin 3 or Monistat-Derm?

By our independent rating, Monistat-Derm scores higher — 3.5 vs 3.4 out of 5 for Gyne-Lotrimin 3. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Gyne-Lotrimin 3 and Monistat-Derm?

Gyne-Lotrimin 3 contains Clotrimazole, while Monistat-Derm contains Miconazole Nitrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.