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GUANFACINE HYDROCHLORIDE vs TRICHLORMETHIAZIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. GUANFACINE HYDROCHLORIDE and TRICHLORMETHIAZIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

guanfacine hydrochloridetrichlormethiazide

Rating

72/100
70/100

Pharmacy pays

~$5.26 /30
—

Type

RX
RX

Active ingredient

GUANFACINE HYDROCHLORIDE
TRICHLORMETHIAZIDE

Manufacturer

Actavis Elizabeth
Watson Labs

Dosage forms

Tablet
Tablet

Drug class

Central Alpha-2 Adrenergic Agonist
—

Boxed warning

None
None

Treats

Attention Deficit Disorder with Hyperactivity, Hypertension
Edema, Heart Failure, Hypertension

Get guanfacine hydrochloridehigher-rated option

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Frequently asked questions

Which is better-rated, Guanfacine Hydrochloride or Trichlormethiazide?

By our independent rating, Guanfacine Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Trichlormethiazide. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Guanfacine Hydrochloride and Trichlormethiazide?

Guanfacine Hydrochloride contains Guanfacine Hydrochloride, while Trichlormethiazide contains Trichlormethiazide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.