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GLYCOPYRROLATE vs ISOPTO ATROPINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. GLYCOPYRROLATE and ISOPTO ATROPINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

$0.21 /mL
$6.87 /mL

Type

RX
RX

Active ingredient

GLYCOPYRROLATE
ATROPINE SULFATE

Manufacturer

Dosage forms

Injectable, Liquid, Solution, Tablet
Solution

Drug class

Anticholinergic
Anticholinergic

Boxed warning

None
None

Treats

Hyperhidrosis, Drug-Induced Abnormalities, Peptic Ulcer
Bradycardia, Heart Arrest, Poisoning

Frequently asked questions

Which is cheaper, Glycopyrrolate or Isopto Atropine?

Glycopyrrolate costs pharmacies less to acquire — about $0.21 vs $6.87 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Glycopyrrolate and Isopto Atropine?

Glycopyrrolate contains Glycopyrrolate, while Isopto Atropine contains Atropine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.