GLUCOTROL vs GLUCOTROL XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	GLUCOTROL	GLUCOTROL XL
Rating	64/100	64/100
Pharmacy pays	~$1.41 /30	~$1.41 /30
Type	RX	RX
Active ingredient	GLIPIZIDE	GLIPIZIDE
Manufacturer	Pfizer	Pfizer
Dosage forms	Tablet	Tablet, extended release
Drug class	Sulfonylurea	Sulfonylurea
Boxed warning	None	None
Half-life	about 2 to 4 hours	about 2 to 4 hours
Treats	Type 2 Diabetes Mellitus	Type 2 Diabetes Mellitus

glucotrol glucotrol xl

Rating

64/100

Pharmacy pays

~$1.41 /30

Type

Active ingredient

GLIPIZIDE

Manufacturer

Pfizer

Dosage forms

Tablet

Tablet, extended release

Drug class

Sulfonylurea

Boxed warning

None

Half-life

about 2 to 4 hours

Treats

Type 2 Diabetes Mellitus

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Frequently asked questions

Which is better-rated, Glucotrol or Glucotrol XL?

Glucotrol and Glucotrol XL are tied at 3.2 out of 5 by our independent rating.

Which is cheaper, Glucotrol or Glucotrol XL?

Pharmacies pay about the same to acquire either one — roughly $1.41 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Glucotrol and Glucotrol XL?

Both Glucotrol and Glucotrol XL share the active ingredient Glipizide.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.