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GLIPIZIDE vs GLUCOTROL XL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Rating

66/100
64/100

Pharmacy pays

~$1.41 /30
~$1.41 /30

Type

RX
RX

Active ingredient

GLIPIZIDE
GLIPIZIDE

Manufacturer

Dosage forms

Tablet, Tablet, extended release
Tablet, extended release

Drug class

Sulfonylurea
Sulfonylurea

Boxed warning

None
None

Half-life

about 2 to 4 hours
about 2 to 4 hours

Treats

Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus

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Frequently asked questions

Which is better-rated, Glipizide or Glucotrol XL?

By our independent rating, Glipizide scores higher — 3.3 vs 3.2 out of 5 for Glucotrol XL. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Glipizide or Glucotrol XL?

Pharmacies pay about the same to acquire either one — roughly $1.41 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Glipizide and Glucotrol XL?

Both Glipizide and Glucotrol XL share the active ingredient Glipizide.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.