GLUCOPHAGE XR vs RIOMET ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	GLUCOPHAGE XR	RIOMET ER
Rating	70/100	New
Pharmacy pays	~$0.74 /30	~$0.74 /30
Type	RX	RX
Active ingredient	METFORMIN HYDROCHLORIDE	METFORMIN HYDROCHLORIDE
Manufacturer	Emd Serono	Sun Pharm
Dosage forms	Tablet, extended release	—
Drug class	Biguanide	Biguanide
Boxed warning	None	None
Half-life	about 6.2 hours (plasma elimination half-life in adults with normal kidney function)	about 6.2 hours (plasma elimination half-life in adults with normal kidney function)
Treats	Type 2 Diabetes Mellitus	Type 2 Diabetes Mellitus

glucophage xr riomet er

Rating

70/100

New

Pharmacy pays

~$0.74 /30

Type

Active ingredient

METFORMIN HYDROCHLORIDE

Manufacturer

Emd Serono

Sun Pharm

Dosage forms

Tablet, extended release

—

Drug class

Biguanide

Boxed warning

None

Half-life

about 6.2 hours (plasma elimination half-life in adults with normal kidney function)

Treats

Type 2 Diabetes Mellitus

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Frequently asked questions

Which is cheaper, Glucophage XR or Riomet ER?

Pharmacies pay about the same to acquire either one — roughly $0.74 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Glucophage XR and Riomet ER?

Both Glucophage XR and Riomet ER share the active ingredient Metformin Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.