GLEOSTINE vs PURINETHOL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. GLEOSTINE and PURINETHOL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	GLEOSTINE	PURINETHOL
Rating	70/100	New
Pharmacy pays	—	~$29.79 /30
Type	RX	RX
Active ingredient	LOMUSTINE	MERCAPTOPURINE
Manufacturer	Azurity	Stason Pharms
Dosage forms	Capsule	Tablet
Drug class	Alkylating Drug	—
Boxed warning	Boxed warning	None
Half-life	about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug	—
Treats	Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease	Non-Hodgkin Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

gleostine purinethol

Rating

70/100

New

Pharmacy pays

—

~$29.79 /30

Type

Active ingredient

LOMUSTINE

MERCAPTOPURINE

Manufacturer

Azurity

Stason Pharms

Dosage forms

Capsule

Tablet

Drug class

Alkylating Drug

—

Boxed warning

None

Half-life

about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug

—

Treats

Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease

Non-Hodgkin Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

Frequently asked questions

What is the difference between Gleostine and Purinethol?

Gleostine contains Lomustine, while Purinethol contains Mercaptopurine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.