GLEOSTINE vs MATULANE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. GLEOSTINE and MATULANE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	GLEOSTINE	MATULANE
Rating	72/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	LOMUSTINE	PROCARBAZINE HYDROCHLORIDE
Manufacturer	Azurity	Leadiant Biosci Inc
Dosage forms	Capsule	Capsule
Drug class	Alkylating Drug	—
Boxed warning	Boxed warning	Boxed warning
Half-life	about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug	—
Treats	Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease	Brain Neoplasms, Hodgkin Disease, Lung Neoplasms

gleostine matulane

Rating

72/100

New

Pharmacy pays

—

Type

Active ingredient

LOMUSTINE

PROCARBAZINE HYDROCHLORIDE

Manufacturer

Azurity

Leadiant Biosci Inc

Dosage forms

Capsule

Drug class

Alkylating Drug

—

Boxed warning

Half-life

about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug

—

Treats

Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease

Brain Neoplasms, Hodgkin Disease, Lung Neoplasms

Frequently asked questions

What is the difference between Gleostine and Matulane?

Gleostine contains Lomustine, while Matulane contains Procarbazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.