GENGRAF vs LOCORTEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. GENGRAF and LOCORTEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	GENGRAF	LOCORTEN
Rating	72/100	70/100
Pharmacy pays	~$52.85 /30	—
Type	RX	RX
Active ingredient	CYCLOSPORINE	FLUMETHASONE PIVALATE
Manufacturer	Abbvie	Novartis
Dosage forms	Capsule	Topical
Drug class	Calcineurin Inhibitor Immunosuppressant	—
Boxed warning	Boxed warning	None
Half-life	about 8.4 hours (range 5 to 18 hours)	—
Treats	Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus	Atopic Dermatitis, Contact Dermatitis, Diaper Rash

gengraf locorten

Rating

72/100

70/100

Pharmacy pays

~$52.85 /30

—

Type

Active ingredient

CYCLOSPORINE

FLUMETHASONE PIVALATE

Manufacturer

Abbvie

Novartis

Dosage forms

Capsule

Topical

Drug class

Calcineurin Inhibitor Immunosuppressant

—

Boxed warning

None

Half-life

about 8.4 hours (range 5 to 18 hours)

—

Treats

Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

Atopic Dermatitis, Contact Dermatitis, Diaper Rash

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Frequently asked questions

Which is better-rated, Gengraf or Locorten?

By our independent rating, Gengraf scores higher — 3.6 vs 3.5 out of 5 for Locorten. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Gengraf and Locorten?

Gengraf contains Cyclosporine, while Locorten contains Flumethasone Pivalate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.