GEMFIBROZIL vs ZETIA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. GEMFIBROZIL and ZETIA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	GEMFIBROZIL	ZETIA
Rating	70/100	70/100
Pharmacy pays	~$3.09 /30	~$2.17 /30
Type	RX	RX
Active ingredient	GEMFIBROZIL	EZETIMIBE
Manufacturer	Cadila Pharms Ltd	Organon
Dosage forms	Tablet	Tablet
Drug class	Peroxisome Proliferator Receptor Alpha Agonist	Dietary Cholesterol Absorption Inhibitor
Boxed warning	None	None
Half-life	—	about 22 hours
Treats	Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias	Hypercholesterolemia, Hyperlipoproteinemia Type II, Familial Combined Hyperlipidemia

gemfibrozil zetia

Rating

70/100

Pharmacy pays

~$3.09 /30

~$2.17 /30

Type

Active ingredient

GEMFIBROZIL

EZETIMIBE

Manufacturer

Cadila Pharms Ltd

Organon

Dosage forms

Tablet

Drug class

Peroxisome Proliferator Receptor Alpha Agonist

Dietary Cholesterol Absorption Inhibitor

Boxed warning

None

Half-life

—

about 22 hours

Treats

Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

Hypercholesterolemia, Hyperlipoproteinemia Type II, Familial Combined Hyperlipidemia

Frequently asked questions

Which is better-rated, Gemfibrozil or Zetia?

Gemfibrozil and Zetia are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Gemfibrozil or Zetia?

Zetia costs pharmacies less to acquire — about $2.17 vs $3.09 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Gemfibrozil and Zetia?

Gemfibrozil contains Gemfibrozil, while Zetia contains Ezetimibe — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.