GABITRIL vs LAMICTAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. GABITRIL and LAMICTAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	GABITRIL	LAMICTAL
Rating	New	70/100
Pharmacy pays	~$63.70 /30	~$4.39 /30
Type	RX	RX
Active ingredient	TIAGABINE HYDROCHLORIDE	LAMOTRIGINE
Manufacturer	Cephalon	Glaxosmithkline
Dosage forms	Tablet	Tablet, Kit
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	Boxed warning
Half-life	—	about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism
Treats	Bipolar Disorder, Partial Epilepsies	Bipolar Disorder, Partial Epilepsies, Seizures

gabitril lamictal

Rating

New

70/100

Pharmacy pays

~$63.70 /30

~$4.39 /30

Type

Active ingredient

TIAGABINE HYDROCHLORIDE

LAMOTRIGINE

Manufacturer

Cephalon

Glaxosmithkline

Dosage forms

Tablet

Tablet, Kit

Drug class

Anti-Epileptic Agent

Boxed warning

None

Boxed warning

Half-life

—

about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism

Treats

Bipolar Disorder, Partial Epilepsies

Bipolar Disorder, Partial Epilepsies, Seizures

Frequently asked questions

Which is cheaper, Gabitril or Lamictal?

Lamictal costs pharmacies less to acquire — about $4.39 vs $63.70 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Gabitril and Lamictal?

Gabitril contains Tiagabine Hydrochloride, while Lamictal contains Lamotrigine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.