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GABAPENTIN vs ZONISADE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. GABAPENTIN and ZONISADE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

~$1.22 /30
~$3.16 /30

Type

RX
RX

Active ingredient

GABAPENTIN
ZONISAMIDE

Dosage forms

Capsule, Solution, Suspension, Tablet
Suspension

Drug class

Anti-Epileptic Agent
Anti-Epileptic Agent

Boxed warning

None
None

Half-life

about 5 to 7 hours in adults with normal kidney function

Treats

Bipolar Disorder, Partial Epilepsies, Phobic Disorders
Partial Epilepsies

Frequently asked questions

Which is cheaper, Gabapentin or Zonisade?

Gabapentin costs pharmacies less to acquire — about $1.22 vs $3.16 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Gabapentin and Zonisade?

Gabapentin contains Gabapentin, while Zonisade contains Zonisamide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.