GABAPENTIN vs LAMICTAL XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. GABAPENTIN and LAMICTAL XR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	GABAPENTIN	LAMICTAL XR
Rating	New	New
Pharmacy pays	~$1.22 /30	~$4.39 /30
Type	RX	RX
Active ingredient	GABAPENTIN	LAMOTRIGINE
Manufacturer	Zhejiang Yongtai	Smithkline Beecham
Dosage forms	Capsule, Solution, Suspension, Tablet	Tablet, extended release, Kit
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	about 5 to 7 hours in adults with normal kidney function	about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism
Treats	Bipolar Disorder, Partial Epilepsies, Phobic Disorders	Bipolar Disorder, Partial Epilepsies, Seizures

gabapentin lamictal xr

Rating

New

Pharmacy pays

~$1.22 /30

~$4.39 /30

Type

Active ingredient

GABAPENTIN

LAMOTRIGINE

Manufacturer

Zhejiang Yongtai

Smithkline Beecham

Dosage forms

Capsule, Solution, Suspension, Tablet

Tablet, extended release, Kit

Drug class

Anti-Epileptic Agent

Boxed warning

None

Half-life

about 5 to 7 hours in adults with normal kidney function

about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism

Treats

Bipolar Disorder, Partial Epilepsies, Phobic Disorders

Bipolar Disorder, Partial Epilepsies, Seizures

Frequently asked questions

Which is cheaper, Gabapentin or Lamictal XR?

Gabapentin costs pharmacies less to acquire — about $1.22 vs $4.39 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Gabapentin and Lamictal XR?

Gabapentin contains Gabapentin, while Lamictal XR contains Lamotrigine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.