FYCOMPA vs HORIZANT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. FYCOMPA and HORIZANT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FYCOMPA	HORIZANT
Rating	New	70/100
Pharmacy pays	~$616.57 /30	—
Type	RX	RX
Active ingredient	PERAMPANEL	GABAPENTIN ENACARBIL
Manufacturer	Catalyst Pharms	Azurity
Dosage forms	Suspension, Tablet	Tablet, extended release
Drug class	Noncompetitive Ampa Glutamate Receptor Antagonist	—
Boxed warning	Boxed warning	None
Half-life	—	about 5 to 7 hours in adults with normal kidney function
Treats	Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures	Bipolar Disorder, Partial Epilepsies, Phobic Disorders

fycompa horizant

Rating

New

70/100

Pharmacy pays

~$616.57 /30

—

Type

Active ingredient

PERAMPANEL

GABAPENTIN ENACARBIL

Manufacturer

Catalyst Pharms

Azurity

Dosage forms

Suspension, Tablet

Tablet, extended release

Drug class

Noncompetitive Ampa Glutamate Receptor Antagonist

—

Boxed warning

None

Half-life

—

about 5 to 7 hours in adults with normal kidney function

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Seizures

Bipolar Disorder, Partial Epilepsies, Phobic Disorders

Frequently asked questions

What is the difference between Fycompa and Horizant?

Fycompa contains Perampanel, while Horizant contains Gabapentin Enacarbil — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.