FYARRO vs KOSELUGO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. FYARRO and KOSELUGO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FYARRO	KOSELUGO
Rating	New	70/100
Pharmacy pays	~$48.61 /30	—
Type	RX	RX
Active ingredient	SIROLIMUS	SELUMETINIB SULFATE
Manufacturer	Aadi	Astrazeneca
Dosage forms	Injectable	Capsule, Powder
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Lymphangioleiomyomatosis, Perivascular Epithelioid Cell Neoplasms	Neurofibromatosis 1

fyarro koselugo

Rating

New

70/100

Pharmacy pays

~$48.61 /30

—

Type

Active ingredient

SIROLIMUS

SELUMETINIB SULFATE

Manufacturer

Aadi

Astrazeneca

Dosage forms

Injectable

Capsule, Powder

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Lymphangioleiomyomatosis, Perivascular Epithelioid Cell Neoplasms

Neurofibromatosis 1

Frequently asked questions

What is the difference between Fyarro and Koselugo?

Fyarro contains Sirolimus, while Koselugo contains Selumetinib Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.