Skip to content
ppharmaranks
Menu

FONDAPARINUX SODIUM vs XARELTO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. FONDAPARINUX SODIUM and XARELTO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$41.88 /mL
$0.98 /mL

Type

RX
RX

Active ingredient

FONDAPARINUX SODIUM
RIVAROXABAN

Dosage forms

Injectable
Powder, Tablet, Kit

Drug class

Factor Xa Inhibitor
Factor Xa Inhibitor

Boxed warning

Half-life

about 5 to 9 hours (11 to 13 hours in older adults)

Treats

Pulmonary Embolism, Venous Thrombosis
Pulmonary Embolism, Venous Thrombosis

Frequently asked questions

Which is cheaper, Fondaparinux Sodium or Xarelto?

Xarelto costs pharmacies less to acquire — about $0.98 vs $41.88 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Fondaparinux Sodium and Xarelto?

Fondaparinux Sodium contains Fondaparinux Sodium, while Xarelto contains Rivaroxaban — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.