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FOCALIN vs RITALIN-SR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. FOCALIN and RITALIN-SR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
70/100

Pharmacy pays

~$46.03 /30
~$18.94 /30

Type

RX
RX

Active ingredient

DEXMETHYLPHENIDATE HYDROCHLORIDE
METHYLPHENIDATE HYDROCHLORIDE

Manufacturer

Dosage forms

Tablet
Tablet, extended release

Drug class

Central Nervous System Stimulant
Central Nervous System Stimulant

Boxed warning

Half-life

about 2.7 hours

Treats

Attention Deficit Disorder with Hyperactivity
Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Frequently asked questions

Which is better-rated, Focalin or Ritalin-SR?

By our independent rating, Ritalin-SR scores higher — 3.5 vs 3.4 out of 5 for Focalin. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Focalin or Ritalin-SR?

Ritalin-SR costs pharmacies less to acquire — about $18.94 vs $46.03 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Focalin and Ritalin-SR?

Focalin contains Dexmethylphenidate Hydrochloride, while Ritalin-SR contains Methylphenidate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.