FML vs HYDROCORTONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. FML and HYDROCORTONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	FML	HYDROCORTONE
Rating	72/100	70/100
Pharmacy pays	$12.87 /mL	$0.15 /g
Type	RX	RX
Active ingredient	FLUOROMETHOLONE	HYDROCORTISONE ACETATE
Manufacturer	Allergan	Merck
Dosage forms	Drops	Injectable, Tablet
Drug class	Corticosteroid	Corticosteroid
Boxed warning	None	None
Half-life	—	about 1.5 hours
Treats	Conjunctivitis, Inflammation, Keratitis	Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

fml hydrocortone

Rating

72/100

70/100

Pharmacy pays

$12.87 /mL

$0.15 /g

Type

Active ingredient

FLUOROMETHOLONE

HYDROCORTISONE ACETATE

Manufacturer

Allergan

Merck

Dosage forms

Drops

Injectable, Tablet

Drug class

Corticosteroid

Boxed warning

None

Half-life

—

about 1.5 hours

Treats

Conjunctivitis, Inflammation, Keratitis

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis

Frequently asked questions

Which is better-rated, Fml or Hydrocortone?

By our independent rating, Fml scores higher — 3.6 vs 3.5 out of 5 for Hydrocortone. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Fml and Hydrocortone?

Fml contains Fluorometholone, while Hydrocortone contains Hydrocortisone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.